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New clinical standards for treating patients with cystic fibrosis (CF) have been released.
A disease, CF affects the lungs and other organs. It is characterized by thick, sticky mucus. CF is always fatal, but thanks to advances in therapy over the last 60 years, life expectancy has increased from a few years to 36 years. Lung [...]]]...
Although imatinib mesylate (Gleevec, Novartis) has been a boon to many patients with chronic myelogenous leukemia, it does not always succeed in prolonging life. But now patients with imatinib resistance may have another reason for hope: tipifarnib (Zarnestra, Johnson & Johnson).
In a phase 1 study at MD Anderson Cancer Center in Houston, Texas, 26 patients [...]]]...
An Early Communication has been issued about varenicline (Chantix, Pfizer), which is approved as an aid to smoking cessation drug. This notice does not mean that the FDA perceives a causal relationship between the drug and the emerging safety problem.
Pfizer recently submitted reports to the agency describing suicidal thoughts in association with the drug. In [...]]]...
Under government pressure, Bayer AG has said it would halt worldwide sales of aprotinin (Trasylol) after a Canadian study found an association with a higher risk of death compared with other drugs.
Aprotinin is used to prevent excessive bleeding during heart bypass surgery.
It blocks enzymes that dissolve blood clots and is designed to stem blood loss [...]]]...
Preschoolers with Attention/Deficit Hyperactivity Disorder (ADHD) are not likely to respond to treatment with the stimulant methylphenidate (e.g., Concerta, McNeil Pediatrics), regardless of the dosage, if they also have three or more coexisting disorders.
These findings were revealed in an analysis from the Preschoolers with ADHD Treatment Study (PATS). Previous PATS results showed that overall, low [...]]]...